In the event you’re deep into the biohacking world like I’m, you’ve in all probability been following Andrew Huberman’s complement routine with laser focus. The Stanford neuroscientist and Huberman Lab podcast host has been refreshingly clear about his NMN supplementation, and after months of analysis, I’ve compiled every little thing it’s essential know.
The Fast Reply:
- Model: Renue by Science NMN
- Dosage: 1-2 grams day by day
- Kind: Sublingual powder
- Timing: Morning, inside 1-2 hours of waking
I’ve been utilizing the identical Renue by Science NMN for years now, and you may save 15% in your order with code BRAINFLOW. Right here’s the total story of Huberman’s NMN journey.
The Tweet That Bought Everybody’s Consideration
On October 24, 2023, Huberman confirmed his model selection with a easy tweet: “I exploit the powdered NMN from Renue by Science.”
However this wasn’t his first time discussing NMN publicly. Again on October 28, 2022, he revealed:
“I began taking it day by day about 4-5 months in the past. I sense 3 results however I can’t make certain it’s the NMN: my hair grows ridiculously quick, vitality elevated (I take it within the morning), slight urge for food discount. Could also be placebo. Individuals additionally like renue by science.“
The subsequent day, he adopted up: “I’ve used Renue NMN in pure powdered kind. I favored it.“
This was large – lastly, a revered scientist sharing his precise model desire with none sponsorship agenda.
The Joe Rogan Deep Dive: Full Protocol Uncovered
Throughout his March 2023 look on JRE, Huberman gave us probably the most detailed breakdown of his NMN protocol up to now:
“I take a reasonably excessive dose. The advice was wherever from 500 milligrams to a few gram and a half. I take a powder and put it below my tongue… I personally take about 2 grams per morning below my tongue.”
He then dropped the precise model bomb: “You should buy it from Renue by Science. I’ve no relationship with Renue by Science… The luggage of it are the easiest way to go as a result of you should buy it in fairly excessive quantity and the luggage are canisters.”
This degree of transparency is precisely why the biohacking neighborhood trusts Huberman.
Present Stack: NMN + NR Combo (2024-2025)
In his AMA #12 episode from October 2023, Huberman revealed he’s truly stacking each NAD+ precursors (for his full complement routine, take a look at Dr. Andrew Huberman’s Complement Listing: The Full Information):
- NMN: 1-2 grams day by day (sublingual powder from Renue by Science)
- NR: 500mg day by day (additionally from Renue by Science)
- Timing: Inside 1-2 hours of waking, half-hour to 2 hours earlier than first meal
- Technique: Holds NMN powder below tongue for 30-45 seconds
“I do certainly take an NR complement day-after-day. I take 500 mg of NR. I additionally, and have individually taken, an NMN complement. I take sublingual NMN. So, I’ll take wherever from 1-2 grams of NMN as a sublingual powder.”
Why Renue by Science Beat Out Different Manufacturers
Right here’s the place it will get fascinating. Huberman initially used Momentous for his NMN, however they discontinued it after the FDA’s 2022 regulatory issues. Whereas many corporations panicked and pulled NMN from their cabinets, Renue by Science stood their floor (for a full comparability of prime NMN manufacturers, see our Greatest NMN Dietary supplements 2025 information).
As Huberman defined:
“Many complement corporations responded to that [FDA ruling] and mentioned ‘okay, we received’t promote it’. Different corporations resembling Renue by Science have continued to promote it.”
For biohackers, this confirmed Renue’s dedication to the NAD+ neighborhood when others bailed.
The Actual Product He Makes use of
Renue by Science presents a number of NMN formulations, however Huberman particularly makes use of their pure NMN powder (β-Nicotinamide Mononucleotide):
- 100g pure powder optimized for sublingual absorption
- Third-party examined for purity and efficiency
- Made in FDA-registered, cGMP-certified amenities
- Zero synthetic components or preservatives
- Greatest value per gram (essential when taking 1-2g day by day!)
In addition they make liposomal NMN capsules for individuals who choose capsules over powder, however Huberman retains it easy with the pure powder.
I’ve personally been utilizing Renue by Science for years, and their high quality has remained persistently wonderful. It can save you 15% on any order with code BRAINFLOW – that provides up whenever you’re taking 1-2 grams day by day like Huberman!
Actual-World Results: What Huberman Really Feels
All through a number of podcasts and tweets, Huberman has persistently reported three major results:
- Power enhance: “Undoubtedly, subjective feeling of a rise in vitality”
- Hair/nail progress: “My hair and nails develop at a ridiculous fee”
- Restoration enhancement: “Restoration from exercises was a lot better”
He takes it early as a result of “it was giving me a whole lot of vitality” – and when he stopped as a management experiment, these advantages pale. That’s some stable n=1 knowledge proper there.
The Disclaimers Each Biohacker Ought to Hear
What I respect most about Huberman is his scientific integrity. He’s crystal clear about:
- Zero monetary ties: “I’ve zero monetary relationship to any firm that manufactures NMN”
- Not for longevity hype: “I don’t take NR and NMN with a view to enhance my lifespan”
- Placebo chance: He admits results could possibly be placebo since human knowledge is proscribed
- Fundamentals first: Dietary supplements can’t repair poor sleep, unhealthy weight loss program, or lack of train
Why Sublingual? The Science of His Technique
Huberman’s selection of sublingual powder isn’t random. This supply methodology:
- Bypasses abdomen acid that may degrade NMN
- Gives superior bioavailability in comparison with capsules
- Delivers sooner absorption straight into bloodstream
- Avoids first-pass liver metabolism
For these of us optimizing each variable, this issues.
Huberman’s NMN Timeline
- Mid-2022: Began day by day NMN supplementation
- October 2022: First public disclosure on Twitter, mentions Renue by Science
- March 2023: Full protocol reveal on Joe Rogan Expertise
- October 2023: Updates protocol in AMA, confirms continued Renue use
- 2024-2025: Maintains 1-2g NMN + 500mg NR day by day stack
The Biohacker’s Takeaway
Huberman’s clear documentation of his NMN journey provides us invaluable knowledge for our personal experiments. His selection of Renue by Science at 1-2 grams day by day represents a considerate method primarily based on each science and private expertise.
However right here’s the important thing: he’s not chasing immortality or making wild claims. He’s merely optimizing his day by day vitality and restoration. That’s the form of grounded biohacking we’d like extra of.
Bear in mind, Huberman at all times emphasizes that no complement can change high quality sleep, correct vitamin, constant train, and stress administration. NMN is only one device within the optimization toolkit – however in the event you’re going to make use of it, no less than now you recognize precisely what one of many world’s main neuroscientists is taking.
Able to strive Huberman’s actual NMN protocol? Get the identical Renue by Science NMN powder he makes use of and save 15% with code BRAINFLOW.
