The noninvasive swept-source anterior-segment optical coherence tomography (SS-ASOCT) can diagnose early-onset childhood glaucoma, in response to a examine printed on-line Might 22 in JAMA Ophthalmology.
Sushmita Kaushik, from the Superior Eye Centre on the Postgraduate Institute of Medical Schooling and Analysis in Chandigarh, India, and colleagues examined using SS-ASOCT in diagnosing pediatric sufferers as having early-onset childhood glaucoma versus not having glaucoma in a potential, comparative examine together with pediatric sufferers youthful than 2 years.
To investigate the visibility of the trabecular meshwork (TM) constructions, the angle opening distance (500 or 250 mm), and the angle recess space (250 or 500 mm2), imaging was carried out utilizing SS-ASOCT with the ‘flying child’ approach.
The SS-ASOCT options had been in contrast between 23 pediatric sufferers with out and 30 with early-onset childhood glaucoma; prognosis was primarily based on an eye fixed examination utilizing an ophthalmoscope.
The researchers discovered that the TM shadow was clearly seen in 100 and 26.7% of sufferers with out glaucoma and with glaucoma, respectively. The very best space underneath the receiver working attribute curve for diagnosing pediatric sufferers as not having glaucoma was 0.87 for a clearly seen TM construction.
Larger anterior chamber angle measurement values had been seen for pediatric sufferers with glaucoma versus these with out glaucoma. In all younger kids with corneal opacity who didn’t have glaucoma, the TM construction was visualized; SS-ASOCT appropriately recognized all 23 sufferers as not having glaucoma.
“The findings recommend using SS-ASOCT provides the potential for distinguishing early-onset childhood glaucoma from different circumstances,” the authors write.
Extra info:
Sushmita Kaushik et al, Utility of Swept-Supply Anterior-Section OCT as an In-Workplace Biomarker for Early Childhood Glaucoma, JAMA Ophthalmology (2025). DOI: 10.1001/jamaophthalmol.2025.1009
Sylvia L. Groth et al, Flying Infants and Swept-Supply OCT—An Modern Approach to Detect Childhood Glaucoma, JAMA Ophthalmology (2025). DOI: 10.1001/jamaophthalmol.2025.1375
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