June 26, 2025
4 min watch
Key takeaways:
- Blood biologics can be utilized for gentle to superior dry eye.
- Autologous serum, platelet-rich plasma and plasma-rich progress elements present pure remedy choices.
MINNEAPOLIS — Blood biologics needn’t be reserved for superior corneal circumstances, Mahnia Madan, OD, FAAO, stated on this Healio Video Perspective from Optometry’s Assembly.
“We don’t have to attend … till sufferers are actually determined or they’re at end-stage illness,” Madan, a companion at Vancouver Eye Physician and the co-owner of MYE Drop, stated.
In her associated lecture, Madan shared research on using biologics in circumstances reminiscent of neurotrophic keratitis, Sjögren’s syndrome and superior dry eye illness.
“However I’ve had some actually nice success utilizing it in sufferers with recurrent corneal erosions with gentle to average dry eye, with sufferers which have had PRK or LASIK and are struggling with dry eyes, and sufferers who simply need pure choices,” she stated within the video.
Madan mentioned autologous serum, platelet-rich plasma (PRP) and plasma-rich progress elements (PRGF) in her lecture.
“Biologics should not that new,” she stated. “Our blood accommodates progress elements. We first used blood in dry eye in 1975 within the type of a finger prick. Sufferers had been requested to prick their finger, put a little bit blood of their eye, and it obtained higher. We figured perhaps not all of the parts had been obligatory, so we got here up with autologous serum in 1984.”
Madan stated autologous serum, PRP and PRGF include barely completely different quantities of progress elements. The affected person’s blood is drawn and centrifuged, and varied strategies result in completely different quantities of ensuing platelets and progress elements.
“PRP and PRGF are thought of barely superior to autologous serum,” Madan stated in her lecture. “However there are not any trials evaluating them. The final consensus is they’re superior of their therapeutic powers.”
When making ready blood biologics to be used within the eye, autologous serum is diluted with saline, whereas PRP and PRGF should not, Madan stated.
On this video, Madan addresses frequent questions on dosing schedules, negative effects, indications and sensible concerns for sufferers.
Sources/Disclosures
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Madan M. Function of blood biologics in dry eye: From AS to PRP to amniotics. Introduced at: Optometry’s Assembly; June 25-28, 2025; Minneapolis.
Disclosures:
Madan studies being co-owner of MYE Drop and having monetary relationships with AbbVie, Alcon, Bausch + Lomb, Labtician, Lumenis, Santen, Solar Pharma, Thea, Valeo and Zeiss.
