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New Eli Lilly drug may assist stop muscle loss whereas taking a GLP-1


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CHICAGO — An investigational remedy from Eli Lilly helped protect lean mass and drive higher lack of fats in sufferers taking the favored weight problems remedy Wegovy.

In a Part 2 trial, sufferers taking the highest-dose mixture of Wegovy and the drug, referred to as bimagrumab, misplaced 22% of their weight at 72 weeks. Ninety-three p.c of that was fats mass, and the remainder was lean mass. Folks taking Wegovy alone misplaced a smaller 16% of their weight, and 72% of that was fats mass, in keeping with outcomes that shall be introduced Monday on the American Diabetes Affiliation assembly.

Sufferers taking the mixture skilled an estimated 58% discount in visceral fats, the kind of fats within the stomach that’s considered significantly dangerous. That compares with a drop of 36% in these taking Wegovy alone.

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