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The NIH Ache Consortium was established to boost ache analysis and promote collaboration amongst researchers throughout the numerous NIH Institutes and Facilities which have applications and actions addressing ache. To this finish, the next objectives have been recognized for the Ache Consortium:
- To develop a complete and forward-thinking ache analysis agenda for the NIH – one which builds on what we have now discovered from our previous efforts.
- To determine key alternatives in ache analysis, significantly those who present for multidisciplinary and trans-NIH participation.
- To extend visibility for ache analysis – each throughout the NIH intramural and extramural communities, in addition to exterior the NIH. The latter audiences embrace our numerous ache advocacy and affected person teams who’ve expressed their pursuits by scientific and legislative channels.
- To pursue the ache analysis agenda by Public-Non-public partnerships, wherever relevant. This underscores a key dynamic that has been bolstered and inspired by the Roadmap course of.
Ache Consortium Members
Government Committee
Dr. Walter Koroshetz
Director, Nationwide Institute of Neurological Problems and Stroke (Chair)
Dr. Lindsey Criswell
Director, Nationwide Institute of Arthritis and Musculoskeletal and Pores and skin Ailments
Dr. Helene Langevin
Director, Nationwide Heart for Complementary and Integrative Well being
Dr. Nora D. Volkow
Director, Nationwide Institute on Drug Abuse
Dr. Shannon Zenk
Director, Nationwide Institute of Nursing Analysis
Institutes and Facilities
Nationwide Institute of Neurological Problems and Stroke (NINDS)
Main Consultant: Dr. Michael Oshinsky
NINDS invests in ache analysis that focuses on the mechanisms of ache related to neurological issues. This contains analysis on central and peripheral mechanisms of ache, ache pathways, circuits and processing. NINDS helps mannequin and system growth, goal discovery and analysis spanning fundamental/ pre-clinical, scientific and translational science.
Be taught extra: Concentrate on Ache Analysis
Nationwide Heart for Complementary and Integrative Well being (NCCIH)
Main Consultant: Dr. Wen Chen
NCCIH’s mission is to find out, by rigorous scientific investigation, the basic science, usefulness, and security of complementary and integrative well being approaches and their roles in bettering well being and well being care. Complementary and integrative approaches embrace dietary, psychological, and bodily interventions. With a powerful deal with nonpharmacologic methods, NCCIH helps analysis that explores how these approaches can enhance ache administration inside a whole-person well being framework. NCCIH additionally leverages cutting-edge biomedical and computational applied sciences to drive elementary, translational, and scientific analysis, selling holistic, preventative well being methods that enhances the well-being of all People. In alignment with nationwide well being priorities, analysis supported by NCCIH goals to tell decision-making by the general public, well being care professionals, and policymakers concerning the built-in use of those approaches.
Be taught extra:
Nationwide Institute of Nursing Analysis (NINR)
Main Consultant: Dr. Karen Kehl
NINR helps ache analysis to boost ache administration throughout the lifespan, with an emphasis on bettering high quality of life for people with acute and power ache. NINR-funded research discover customized ache administration methods, symptom science and palliative care. The institute prioritizes entry to efficient ache care.
Be taught extra: NINR Dwelling Web page
Nationwide Institute of Dental and Craniofacial Analysis (NIDCR)
Main Consultant: Dr. Melissa Ghim
NIDCR helps analysis on ache circumstances pertaining to the oral and craniofacial area. This contains research on temporomandibular issues (TMDs), neuropathic ache, ache following dental procedures, oral most cancers ache, and ache associated to oral most cancers remedies. NIDCR emphasizes understanding peripheral and central ache mechanisms, from the event and upkeep of power ache to its endogenous decision and/or disruption. The Institute additionally prioritizes the event of novel diagnostic and therapeutic interventions, modeling, prevention analysis, and different ache administration approaches related to the ache circumstances of curiosity to finally enhance affected person outcomes.
Be taught extra: Ache (oral, facial)
Nationwide Institute on Drug Abuse (NIDA)
Main Consultant: Dr. Will M. Aklin
NIDA helps analysis on the intersection of ache and substance use, together with the event of safer ache administration methods to scale back the chance of opioid misuse and habit. NIDA funds research on ache therapy, the neurobiology of ache and habit, and methods to stop and deal with opioid use dysfunction in sufferers with power ache.
Be taught extra: Power Ache Overview
Nationwide Most cancers Institute (NCI)
Main Consultant: Dr. Rachel Altshuler
NCI helps preclinical, translational, and scientific analysis on cancer-related ache attributable to malignancies, diagnostic procedures, and cancer-directed remedies. This contains chemotherapy-induced peripheral neuropathy, tumor related ache, surgical ache, power ache syndromes and phantom ache. NCI emphasizes bettering ache administration and high quality of life for most cancers sufferers and survivors.
Be taught extra: Aspect Impact of Most cancers – Ache
Nationwide Institute on Growing old (NIA)
Main Consultant: Dr. Dave Frankowski
NIA focuses on power ache in getting old populations, who’re disproportionately affected by pain-related circumstances. Analysis priorities embrace understanding mechanisms underlying the ache expertise with getting old; enhancing evaluation, prevention, and administration methods for ache in midlife and older adults; and bettering the well being of midlife and older adults getting old populations affected by ache. NIA additionally helps research on ache notion and administration in people with Alzheimer’s illness and associated dementias.
Be taught extra:
Nationwide Institute of Baby Well being and Human Improvement (NICHD)
Main Representatives: Dr. Sue Marden and Dr. Helena Ahn
NICHD helps analysis on ache administration in neonatal and pediatric care, ache associated to gynecological circumstances, and rehabilitation for people with bodily impairments. The institute prioritizes ache administration for critically sick and injured kids, ache mechanism and administration of gynecologic circumstances together with endometriosis-associated ache, vulvodynia/vestibulodynia, dysmenorrhea, power pelvic ache, and different gynecologic ache syndromes, acute and power ache administration of individuals with bodily and mental disabilities, and protected and efficient ache remedies throughout labor, childbirth, and postpartum care.
Be taught extra: NICHD Dwelling Web page
Nationwide Institute of Arthritis and Musculoskeletal and Pores and skin Ailments (NIAMS)
Main Consultant: Dr. Rebecca Lenzi
NIAMS helps analysis on ache associated to bones, joints, muscle groups, and pores and skin. This contains learning ache mechanisms in circumstances like arthritis, lupus, and fibromyalgia, in addition to bettering ache administration for musculoskeletal and pores and skin issues. NIAMS goals to develop efficient therapies to scale back ache and enhance high quality of life.
Be taught extra: NIAMS Ache Analysis
Nationwide Institute of Psychological Well being (NIMH)
Main Consultant: Dr. Alex Talkovsky
NIMH is excited about analysis learning the interactions between psychological sicknesses and co-occurring circumstances to offer extra perception into the causes and facilitators of psychological sicknesses, in addition to present pathways to enhance the availability of interventions and companies to finally stop and deal with psychological sickness and comorbidities and obtain higher outcomes for individuals with psychological sicknesses. NIMH works with different NIH institutes and facilities to help analysis to handle treatable medical comorbidities linked to untimely mortality amongst individuals with critical psychological sickness.
Be taught extra: Power Sickness & Psychological Well being
Nationwide Eye Institute (NEI)
Main Consultant: Dr. Houmam Araj
NEI helps analysis on pan associated to ocular circumstances, together with dry eye illness, post-surgical ache, and neuropathic ocular ache. Analysis focuses on understanding ache mechanisms within the eye and creating remedies to alleviate visual-system associated ache.
Be taught extra: NEI Dwelling Web page
Nationwide Institute of Normal Medical Sciences (NIGMS)
Main Consultant: Dr. Zuzana Justinova
NIGMS funds fundamental analysis geared toward understanding the ideas, mechanisms, and organic processes that underlie residing organisms. NIGMS additionally helps analysis in a number of particular scientific areas that embrace anesthesiology and ache throughout and after surgical procedures. Research of ache embrace analysis on organic mechanisms concerned within the transition of acute to power postsurgical ache and its decision, in addition to perioperative ache administration.
Be taught extra: NIGMS Dwelling Web page
Nationwide Institute of Diabetes and Digestive and Kidney Problems (NIDDK)
Main Consultant: Dr. Christopher Mullins
NIDDK helps broad fundamental, translational, and scientific analysis and growth of recent measures, instruments, remedies, and analytic approaches that handle essential questions of ache as a part of diabetic neuropathy; digestive illnesses, dietary issues, and weight problems; in addition to kidney, urologic, and hematologic illnesses. Particular NIDDK issues of key significance embrace, however aren’t restricted to: Power inflammatory illnesses of the pancreas and biliary tract; purposeful gastrointestinal and motility issues, similar to irritable bowel syndrome, non-ulcerative dyspepsia, gastroparesis, and purposeful gallbladder dysfunction; inflammatory bowel illness; diabetic neuropathy; polycystic kidney illness; porphyria issues; priapism; urinary stone illness and ureteral stent related ache; and urologic power pelvic ache syndrome. Research proposing multi-disciplinary approaches and experience that observe upon current advances and leverage distinctive methodologies or sources and efforts to tell new scientific methods for bettering ache administration and outcomes in affected affected person populations, each adults and youngsters, are emphasised.
Be taught extra: NIDDK Dwelling Web page
Nationwide Institute on Alcohol Abuse and Alcoholism (NIAAA)
Main Consultant: Dr. Mark Egli
NIAAA helps mechanistic, translational, therapy and prevention analysis on the bi-directional relationship between alcohol use and ache over the lifespan because it impacts power ache outcomes and alcohol misuse.
Be taught extra:
Nationwide Institute on Minority Well being and Well being Disparities (NIMHD)
Main Consultant: Dr. Arundhati Gogineni
Be taught extra: NIMHD Dwelling Web page
Nationwide Institute of Biomedical Imaging and Bioengineering (NIBIB)
Main Representatives: Dr. Michael Wolfson and Dr. Tatjana Atanasijevic
NIBIB helps the event of superior medical imaging and bioengineering applied sciences for ache analysis and therapy. This contains wearable units, imaging methods to visualise ache pathways, and progressive medical applied sciences to enhance ache interventions.
Be taught extra: NIBIB Dwelling Web page, NIH HEAL Initiative and NIBIB, and Science Training Matters
Nationwide Institute on Deafness and Different Communication Problems (NIDCD)
Be taught extra: NIDCD Dwelling Web page
Nationwide Heart for Advancing Translational Sciences (NCATS)
Main Consultant: Dr. Yolanda Vallejo
Be taught extra: NCATS Dwelling Web page
Nationwide Coronary heart, Lung, and Blood Institute (NHLBI)
Main Representatives: Dr. Brian Bai and Dr. Phil Tonkins
NHLBI helps analysis on ache associated to cardiovascular, pulmonary, and hematologic circumstances, significantly sickle cell illness, in addition to ache administration methods for sufferers present process cardiac, lung, and bone marrow transplant surgical procedures and different therapy procedures.
Be taught extra: NHLBI Well being Matters
John E. Fogarty Worldwide Heart (FIC)
Be taught extra: Fogarty Heart Dwelling Web page
Warren Grant Magnuson Scientific Heart (CC)
Main Consultant: Dr. Andrew Mannes
Be taught extra: Scientific Heart Dwelling Web page
Workplace of the Director
Workplace of Behavioral and Social Sciences Analysis (OBSSR)
Main Consultant: Dr. Wendy Smith
Workplace of Know-how Switch (OTT)
Main Consultant: Dr. Mark Rohrbaugh
Workplace of Analysis on Girls’s Well being (ORWH)
Main Consultant: Dr. David Thomas
ORWH helps analysis on intercourse variations in ache notion, prevalence, and therapy. This contains learning ache circumstances that disproportionately have an effect on girls, similar to power pelvic ache. ORWH additionally promotes the inclusion of girl throughout the life course (e.g. throughout puberty, being pregnant, menopause, …) in ache analysis to enhance understanding and develop tailor-made ache administration methods.
