June 06, 2025
1 min watch
SALT LAKE CITY — On this video, Jay Chhablani, MD, professor of ophthalmology at College of Pittsburgh Faculty of Medication, discusses a preliminary examine of mixture gene remedy focusing on neovascular age-related macular degeneration.
The remedy, a mixture of AIBP, apoA-I and aflibercept, confirmed promise in a mouse examine introduced on the ARVO assembly, Chhablani stated.
“This mix of this triple gene remedy might overcome the anti-VEGF resistance in addition to enhance outcomes,” Chhablani stated.
Reference:
- Ahir M, et al. Mixture gene remedy of AIBP, apoA-I, and aflibercept overcomes anti-VEGF resistance and suppresses fibrosis in neovascular AMD. Introduced at: Affiliation for Analysis in Imaginative and prescient and Ophthalmology assembly; Might 4-8, 2025; Salt Lake Metropolis.
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