Vertex misses on earnings and pauses mRNA cystic fibrosis trial


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Adam Feuerstein is a senior author and biotech columnist, reporting on the crossroads of drug improvement, enterprise, Wall Road, and biotechnology. He’s additionally a co-host of the weekly biotech podcast The Readout Loud and writer of the publication Adam’s Biotech Scorecard. You possibly can attain Adam on Sign at stataf.54.

Vertex Prescribed drugs on Monday reported disappointing first-quarter earnings impacted by weaker-than-expected gross sales of its medication for cystic fibrosis, and little or no contributions from a gene remedy for sickle cell illness and a not too long ago launched ache drugs. 

A “tolerability concern” brought on a brief pause to an early stage research involving a carefully watched, inhaled, mRNA-based remedy for cystic fibrosis, the corporate mentioned. 

Vertex shares fell 3% in after-hours buying and selling, as traders thought of a inventory buying and selling close to its all-time excessive with an extended look ahead to its subsequent leg of progress. 

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