New analysis in Diabetes, Weight problems and Metabolism reveals that metformin, a drugs historically prescribed to deal with diabetes, is linked to decrease dangers of dementia and early loss of life.
Within the research by investigators at Taipei Medical College that included 452,777 adults with various levels of chubby and weight problems, 35,784 circumstances of dementia and 76,048 deaths occurred over 10 years. Metformin customers exhibited considerably decrease dangers of each dementia and all-cause loss of life than nonusers.
The advantages of metformin have been seen throughout all classes of chubby, weight problems, and extreme weight problems, with 8–12% decrease dangers of dementia and 26–28% decrease dangers of loss of life.
“Though our research outcomes are promising for metformin‘s results on dementia and mortality, additional analysis is required to discover the mechanisms concerned,” stated co-corresponding writer Chiehfeng Chen, MD, Ph.D., MPH.
Extra data:
Protecting Impact of Metformin In opposition to Dementia in Sufferers With Weight problems: Outcomes From a International Federated Well being Community Evaluation, Diabetes Weight problems and Metabolism (2025). DOI: 10.1111/dom.16647
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A diabetes drug might assist stop dementia (2025, August 6)
retrieved 6 August 2025
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