Individuals who have survived most cancers as kids are at larger danger of growing extreme COVID-19, even a long time after their prognosis. That is proven by a brand new examine from Karolinska Institutet printed within the journal The Lancet Regional Well being—Europe.
Due to medical advances, increasingly more kids are surviving most cancers. Nevertheless, even lengthy after remedy has ended, well being dangers might stay. In a brand new registry examine, researchers investigated how grownup childhood most cancers survivors in Sweden and Denmark have been affected by the COVID-19 pandemic.
The examine included over 13,000 individuals who had been identified with most cancers earlier than the age of 20 and who have been no less than 20 years outdated when the pandemic started. They have been in contrast with each siblings and randomly chosen people from the inhabitants of the identical gender and 12 months of delivery.
The outcomes present that childhood most cancers survivors had a decrease danger of contracting COVID-19, however have been 58% extra prone to develop extreme illness in the event that they did change into contaminated. Extreme COVID-19 was outlined because the affected person receiving hospital care, intensive care or loss of life associated to the an infection.
“It is very important perceive that although these people weren’t contaminated extra typically, the implications have been extra critical once they did change into in poor health,” says Javier Louro, postdoctoral researcher on the Institute of Environmental Medication at Karolinska Institutet and first writer of the examine.
The variations in danger have been notably clear during times of excessive transmission, equivalent to when new virus variants equivalent to alpha and omicron unfold quickly. In Sweden, the place pandemic administration was based mostly extra on suggestions than restrictions, the rise in danger was larger than in Denmark, which launched early and strict measures.
“Our outcomes recommend that childhood most cancers survivors ought to be thought-about a danger group in future pandemics or different well being crises. This might contain prioritizing them for vaccination or providing particular safety during times of excessive transmission,” says Louro.
The examine was performed in collaboration with the Danish Most cancers Institute.
Extra data:
COVID-19 an infection and severity amongst childhood most cancers survivors in Denmark and Sweden: a register-based cohort examine, The Lancet Regional Well being – Europe (2025). DOI: 10.1016/j.lanepe.2025.101363
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Adults who survived childhood most cancers are at elevated danger of extreme COVID-19, says new examine (2025, July 4)
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