
Well being officers need you to assume twice earlier than shopping for a kind of brightly coloured little bottles usually offered at gasoline stations, comfort shops and smoke retailers.
Typically known as “gasoline station heroin,” the merchandise are normally marketed as vitality photographs or cognitive dietary supplements however truly include tianeptine, an unapproved drug that may be addictive and carries dangers of significant negative effects.
U.S. poison management facilities have reported a gentle rise in calls linked to the drug for greater than a decade. And final month the Meals and Drug Administration despatched a warning to well being professionals about “the magnitude of the underlying hazard or these merchandise.”
Here is what to find out about gasoline station heroin.
How are these merchandise offered within the U.S.?
Tianeptine is authorized in a quantity international nations as an antidepressant, normally as a low-dose tablet taken thrice a day. But it surely has by no means been authorized by the FDA for any medical situation within the U.S.
Moreover, the drug can’t legally be added to meals and drinks or offered as a dietary complement—one thing the FDA has repeatedly warned U.S. corporations about.
Nonetheless, under-the-radar corporations promote tianeptine in numerous formulation, usually with model names like Zaza, Tianaa, Pegasus and TD Crimson. Though that’s technically unlawful, the FDA doesn’t preapprove components added to dietary supplements and drinks.

“It is type of this gray space of shopper merchandise, or dietary supplements, the place the contents aren’t regulated or examined the way in which they’d be with a medicine,” stated Dr. Diane Calello of the New Jersey Poison Data and Schooling System.
Final 12 months, Calello and her colleagues printed a examine documenting a cluster of emergency calls in New Jersey tied to a flavored elixir known as Neptune’s Repair. Individuals skilled misery, speedy heartbeat, low blood stress and seizures after ingesting it. Greater than a dozen of the 20 sufferers needed to be admitted for intensive care.
Why use these merchandise?
Many tianeptine merchandise declare— with out proof or FDA approval— to assist customers deal with medical circumstances, together with habit, ache and despair.
In 2018, the FDA issued a warning letter to the maker of a product known as Tianna, which claimed to offer “an unparalleled answer to cravings for opiates.”

Whereas tianeptine just isn’t an opioid, the drug binds to a number of the similar receptors within the mind, which may briefly produce results akin to oxycodone and different opioids. Tianeptine additionally carries a number of the similar physiological dangers of opioids, together with the potential to dangerously depress respiration.
“That is what tends to get folks into hassle,” stated Dr. Hannah Hays of Nationwide Youngsters’s Hospital in Columbus, Ohio. “They use it for opioid-like results or to self-treat opioid withdrawal and that may result in gradual respiration and issues like that.”
Individuals coping with opioid habit, ache, despair, nervousness and different circumstances ought to see a well being skilled to get a prescription for FDA-approved therapies, Hays stated.
Is tianeptine use going up?
Consultants aren’t positive however nationwide figures present an enormous rise in emergency calls involving the drug.

Calls to poison management facilities elevated 525% between 2018 and 2023, in response to a knowledge evaluation printed earlier this 12 months. In about 40% of circumstances, the particular person needed to search medical care, with greater than half of them needing crucial care.
One rationalization for the rise in calls is solely that extra Individuals are utilizing the merchandise.
However consultants additionally say that the merchandise are triggering extra emergencies as they develop into stronger and harmful. And the researchers in New Jersey who analyzed Neptune’s Repair discovered that the liquid additionally contained artificial hashish and different medication.
“You by no means fairly know what’s in that bottle,” Calello stated. “It is necessary for folks to know that even when they’ve used a product earlier than, they might get a bottle that accommodates one thing very completely different from what they’re in search of.”

Are there insurance policies that might scale back tianeptine use?
Tianeptine just isn’t included within the federal Managed Substances Act, which bans or restricts medication that don’t have any medical use or have a excessive potential for abuse, resembling heroin, LSD and PCP. However a few dozen states have handed legal guidelines prohibiting or proscribing tianeptine, together with Alabama, Georgia, Michigan, Minnesota, Ohio and Tennessee.
In some circumstances, these legal guidelines have led to extra circumstances of withdrawal amongst customers of tianeptine, which may be chemically addictive. However state knowledge additionally reveals some success in decreasing hurt tied to the drug.
Till lately, Alabama had the best price of tianeptine-related calls within the southern U.S., which elevated greater than 1,400% between 2018 to 2021. However after the state restricted tianeptine in 2021 calls started modestly reducing whereas calls throughout different southern states continued to climb.
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‘Fuel station heroin’ is technically unlawful and extensively out there. Listed below are the details (2025, June 15)
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