Key takeaways:
- Residence OCT could assist sufferers obtain prolonged dosing intervals by way of constant fluid analysis.
- Scans are reviewed by AI by way of a cloud-based platform and by the ophthalmologist.
FORT LAUDERDALE, Fla. — Residence OCT presents customized insights on therapy response for moist age-related macular degeneration which will assist scale back therapy burden, in response to a speaker.
Whereas second-generation anti-VEGF brokers permit for prolonged dosing intervals longer than what’s on label for a lot of sufferers, not all sufferers might be prolonged, Judy E. Kim, MD, FARVO, FASRS, mentioned on the Retina World Congress.
Picture: Anthony DeFino | Healio
“When a affected person is switched from first era to second era and even inside second era, we have no idea how lengthy they are often prolonged, and they don’t final so long as treatment-naive sufferers,” she mentioned. “Lastly, after we do these extensions, what in regards to the different eye?”
Residence OCT gadgets, together with the Scanly Residence OCT system (Notal Imaginative and prescient), permit for a extra individualized therapy method for every affected person.
“It would give us customized, exact information, the place sufferers carry out their scans every day. Then it’s processed by a proprietary synthetic intelligence algorithm,” Kim mentioned. “We get temporal information over time on the place fluid accumulates.”
Kim outlined the essential workflow for a house OCT program. After the referred affected person is assisted with setup by a monitoring middle, affected person scans are repeatedly uploaded to an AI-powered cloud service for evaluation by each AI and the ophthalmologist.
“If we assessment the photographs each 30 days, the retina specialist will get reimbursed,” Kim mentioned.
In response to Kim, sufferers enrolled in a research had been in a position to scan at a imply fee of 6.2 scans per week, with 91.2% of scans eligible for AI evaluation.
“Earlier than using residence OCT, the common interval for therapy was 8 weeks,” she mentioned. “Following incorporation of residence OCT, it was prolonged to fifteen weeks — nearly double — so we’d be capable to scale back therapy burden for our sufferers.”
Extra information confirmed a 43% discount in therapy burden in 29 eyes with moist AMD.
Through the initiation section, fluid analysis with residence OCT will help separate sure therapies based mostly on affected person response. This enables the ophthalmologist to increase therapies that the affected person responded to positively. It could possibly additionally assist decide the proper time to soundly cease therapy and monitor the affected person, in response to Kim.
“We don’t must guess anymore as a result of we are going to see when the fluid reaccumulates, and that’s after we can seize and have the affected person are available in for therapy,” Kim mentioned. “So, there’s a steady security internet, with out having the affected person keep moist within the fluid longer than they need to. And whereas we’re lowering the therapy burden on the handled eye, we will additionally detect conversion within the fellow eye that’s beginning with intermediate AMD.”
References:
- Heier JS, et al. J Vitreoretin Dis. 2024;doi:10.1177/24741264241302858.
- Holekamp NM, et al. Retina. 2024;doi:10.1097/IAE.0000000000004167.
Sources/Disclosures
Collapse
Kim JE. Function of residence OCT in nAMD administration. Introduced at: Retina World Congress; Could 8-11, 2025; Fort Lauderdale, Florida.
Disclosures:
Kim stories beforehand being a researcher for Notal Imaginative and prescient.
