Key takeaways:
- Atrium Well being’s Monetary Toxicity Tumor Board has helped sufferers save tens of millions in copays and drugs prices.
- This system has addressed lack of employee-based insurance coverage, lack of housing and extra.
A affected person with acute myeloid leukemia visited Atrium Well being deeply involved, however not about their illness.
They’d acquired a $50,000 invoice and had no thought what to do about it. When physicians checked out it, they’d questions, too.

Information derived from Knight TG, et al. J Natl Compr Canc Netw. 2025;doi:10.6004/jnccn.2025.7010.
The affected person had been billed for next-generation sequencing. When the affected person’s physicians first inquired in regards to the process to the insurance coverage firm, they have been instructed they didn’t want prior authorization.
The insurance coverage firm then denied the affected person’s declare citing medical necessity.
Physicians introduced the case to Atrium’s Monetary Toxicity Tumor Board (FTTB).
“As soon as we knew there was one case, we knew there was going to be tons of, and that’s precisely what we discovered,” Thomas G. Knight, MD, scientific affiliate professor of hematology and oncology at Wake Forest College College of Drugs and chair of the FTTB at Atrium Well being Levine Most cancers Institute, instructed Healio. “We had discovered one thing like $3 million to $5 million price of payments that have been going to sufferers that we have been unaware of as a result of [the insurance had been doing this].”
Employees at Atrium subsequently addressed the issue and their sufferers now not obtain comparable payments.
Atrium’s FTTB, a first-of-its-kind institutional intervention program, has dealt with greater than 70 instances since its inception in 2019. It has supplied particular person help and carried out systemwide modifications to profit sufferers.
Moreover, the FTTB’s pharmacy-based affected person help program has supplied greater than $10 million in copay help and practically $393 million in free drugs to 1000’s of sufferers, in keeping with knowledge revealed in Journal of the Nationwide Complete Most cancers Community.
“Once we take into consideration the monetary considerations related to most cancers care, we as clinicians, as individuals who take care of relations with most cancers, really feel like this drawback is so large and so huge that there are restricted issues we will do to essentially have an effect on change on this challenge,” Knight stated. “With the event of the [FTTB], we now have lastly recognized a approach to go after this challenge from its very coronary heart, and to leverage all the dedicated and motivated folks all through the most cancers heart to assist.”
‘A number of angles’
Monetary toxicity is a major concern amongst people with most cancers.
Healio beforehand reported on a research that discovered greater than 90% of people with most cancers need to speak in regards to the prices of care with their oncologists.
A number of research even have discovered elevated prices to be a barrier to care.
Healio reported on one which confirmed sufferers with high-deductible insurance policy had shorter OS and cancer-specific survival than those that didn’t.
Ruben A. Mesa, MD, FACP, president and government director at Atrium Well being Wake Forest Baptist Complete Most cancers Middle and senior vp at Atrium Well being, has seen girls with breast most cancers forgo adjuvant radiation remedy as a result of they may not afford to overlook work or journey for his or her remedy.

Ruben A. Mesa
“A variety of instances, the oldsters who’re affected by these points are those you don’t learn about,” Knight stated. “They’re those who didn’t present as much as the clinic, and also you don’t know why. They’re the folks for whom the treatment didn’t work, and you may’t work out why, as a result of it was the fitting remedy. It was as a result of they have been stretching or not filling prescriptions as a result of they couldn’t afford it, and so they have been frightened about speaking about it.”
ASCO not too long ago made seven suggestions to cut back prices to sufferers, together with elimination of copay accumulator adjustor packages and a cap on Medicare Half B.
“Monetary toxicity is a big challenge for sufferers with most cancers on so many ranges, each the bills related to care resembling drugs and copays, and plenty of different elements that relate to receiving care, resembling transportation and lodging,” Mesa stated. “Then there may be the influence by way of employment, or influence on the employment of the partner or the caregiver. It hits folks from a number of angles.”
Want ‘decision-makers’
Monetary navigation packages have helped mitigate monetary toxicity during the last a number of years, however Knight, Mesa and colleagues sought a approach to assist sufferers on a broader scale.
“We already had the mannequin of bringing all these disparate folks from a most cancers heart collectively to repair an issue. It was a tumor board,” Knight stated. “That’s what we do for illnesses. Why don’t we do the identical factor for a difficulty we all know impacts each single affected person within the most cancers heart?”
Representatives from monetary navigation, the billing workplace, nursing navigation, scientific management and administration have to be current at each FTTB case.
“Once we began this, the one rule we had was that it’s a must to have decision-makers within the room,” Knight stated. “You may’t simply have a gathering like this after which return and ask 20 folks, ‘What now? What can we do?’ We wanted the precise decision-makers to have the ability to have an effect on change.”
The once-monthly assembly has continued to develop, with between 70 and 100 folks now attending.
They’ve tackled points resembling out-of-state insurance coverage, undocumented sufferers, lack of employee-based insurance coverage, lack of housing, program denials, Medicaid {qualifications}, coordination points with different suppliers like Veterans Affairs, survivorship prices and extra.
“Sadly, there isn’t any scarcity of examples of people the place monetary toxicity impacts their care,” Mesa stated.
The FTTB has recognized three case patterns: particular person, system-level and legislative.
“The 70 [cases represent] the people who have been mentioned on the large tumor board assembly, however there’s 1000’s of sufferers who’re benefiting,” Knight stated.
For instance, the FTTB helped a 30-year-old affected person with metastatic most cancers obtain help with meals and transportation after dropping employee-based insurance coverage.
This challenge might have an effect on many sufferers, although.
To remain forward of the issue, Atrium created a brand new screening course of for people with metastatic illness or have change into metastatic so they may get to monetary navigation faster.
“I’ve been working this tumor board and taking part on this tumor board for five years, and I’ve discovered one thing new each single time we do it,” Knight stated. “Like something in medication, it requires fixed studying and staying on prime of every part, and nobody particular person can try this. This cooperative mannequin is one which I feel has numerous energy in that it permits you to have consultants in every of the completely different areas, be it drug reimbursement, charity care or transportation.”
‘That is what medication is’
Knight’s curiosity in monetary toxicity started greater than a decade in the past, when he heard Scott Ramsey, MD, PhD, director of Hutchinson Institute for Most cancers Outcomes Analysis at Fred Hutch Most cancers Middle, current research findings at ASCO.
In 2013, Ramsey and colleagues revealed a report in Well being Affairs exhibiting a person with most cancers to be 2.65 instances extra prone to go bankrupt than somebody with out most cancers.
In 2016, they revealed a report in Journal of Medical Oncology that confirmed sufferers with most cancers who go bankrupt had an 80% better threat for dying than those that didn’t.
“I keep in mind being within the viewers for that research and being like, that is what I need to do with my life,” Knight stated. “I need to attempt to go after this drawback.”
But, regardless of quite a few research, Knight nonetheless sees shortfalls in managing monetary toxicity.
“We don’t do one of the best job on this nation screening for that,” he stated. “It’s often a requirement factor.”
Healio beforehand reported on outcomes that discovered monetary toxicity screening could also be achieved with two questions.
“It’s more and more a part of your job,” Knight stated. “I’ve been requested, ‘How does it really feel doing this? Does this really feel out of what you educated for?’ On the finish of the day, that is what medication is now. You are attempting your greatest to navigate this method, to have the ability to ship care in one of the best ways that you would be able to.”
“Individuals typically assume that assets are solely there for people who’ve very low incomes or are at federal poverty degree. That really will not be the case,” Mesa added. “A few of these therapies can rapidly bounce to five-, six-, and God forbid, typically seven-figure therapies that only a few are capable of afford. One doesn’t must be at 300% of the federal poverty degree to qualify for these packages.”
Mesa emphasised the significance of physicians and well being care staff gaining experience in rebates drug corporations could have, in addition to assets out there at metropolis, county, state and federal ranges so they’re ready once they have a affected person in want.
Establishments additionally might observe Atrium’s lead and develop their very own FTTB.
Knight receives a pair calls a month from physicians wanting extra info. Nevertheless, it requires administrative help to get began.
Resolution-makers could get behind it in the event that they see the monetary “boon” FTTB might present, Knight stated.
Knight and colleagues plan to publish a paper sooner or later detailing the institutional value financial savings of their FTTB.
He detailed one 6-week replace that discovered $1.6 million in potential misplaced fees from insurance coverage denials that obtained billed to sufferers as a substitute. Atrium already reversed $200,000 of these denials.
Moreover, researchers calculated $1.8 million in future income from remedy that might have been misplaced if they’d not found the denials.
“For an establishment, it’s not simply the one invoice the affected person has,” Knight stated. “If that is nonpaid, then it’s going to repeat. This isn’t a discrete occasion. Sufferers with most cancers require remedy, and so they require many months of remedy. This stuff will proceed to repeat in case you don’t repair them on the entrance finish.
“What we’ve proven right here with these numbers, and with the large quantity of sufferers we’ve helped, is that it’s potential it is a mannequin that’s simply performed in a wide range of completely different methods,” he added. “I feel this must be the mannequin going ahead for people on this nation.”
References:
For extra info:
Thomas G. Knight, MD, might be reached at thomas.knight@advocatehealth.org.
Ruben A. Mesa, MD, FACP, might be reached at ruben.mesa@advocatehealth.org.